Cargando…

9-cis-13,14-Dihydroretinoic Acid Is an Endogenous Retinoid Acting as RXR Ligand in Mice

The retinoid X receptors (RXRs) are ligand-activated transcription factors which heterodimerize with a number of nuclear hormone receptors, thereby controlling a variety of (patho)-physiological processes. Although synthetic RXR ligands are developed for the treatment of various diseases, endogenous...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rühl, Ralph, Krzyżosiak, Agnieszka, Niewiadomska-Cimicka, Anna, Rochel, Natacha, Szeles, Lajos, Vaz, Belén, Wietrzych-Schindler, Marta, Álvarez, Susana, Szklenar, Monika, Nagy, Laszlo, de Lera, Angel R., Krężel, Wojciech
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451509/ https://www.ncbi.nlm.nih.gov/pubmed/26030625 http://dx.doi.org/10.1371/journal.pgen.1005213

Ejemplares similares

Vitamin A5/X, a New Food to Lipid Hormone Concept for a Nutritional Ligand to Control RXR-Mediated Signaling
por: Krężel, Wojciech, et al.
Publicado: (2021)

Regulation of Retinoid-Mediated Signaling Involved in Skin Homeostasis by RAR and RXR Agonists/Antagonists in Mouse Skin
por: Gericke, Janine, et al.
Publicado: (2013)

Vitamin A5/X controls stress-adaptation and prevents depressive-like behaviors in a mouse model of chronic stress
por: Krzyżosiak, Agnieszka, et al.
Publicado: (2021)

Solution Structures of PPARγ2/RXRα Complexes
por: Osz, Judit, et al.
Publicado: (2012)

Molecular determinants of MED1 interaction with the DNA bound VDR–RXR heterodimer
por: Belorusova, Anna Y, et al.
Publicado: (2020)

Reduced Carotenoid and Retinoid Concentrations and Altered Lycopene Isomer Ratio in Plasma of Atopic Dermatitis Patients
por: Lucas, Renata, et al.
Publicado: (2018)

Research Resource: Transcriptome Profiling of Genes Regulated by RXR and Its Permissive and Nonpermissive Partners in Differentiating Monocyte-Derived Dendritic Cells
por: Széles, Lajos, et al.
Publicado: (2010)

Molluscan RXR Transcriptional Regulation by Retinoids in a Drosophila CNS Organ Culture System
por: de Hoog, Eric, et al.
Publicado: (2022)

A retinoid X receptor (RXR)-selective retinoid reveals that RXR-α is potentially a therapeutic target in breast cancer cell lines, and that it potentiates antiproliferative and apoptotic responses to peroxisome proliferator-activated receptor ligands
por: Crowe, David L, et al.
Publicado: (2004)

Molecular Characterization of RXR (Retinoid X Receptor) Gene Isoforms from the Bivalve Species Chlamys farreri
por: Lv, Jia, et al.
Publicado: (2013)

Structural Basis of Natural Promoter Recognition by the Retinoid X Nuclear Receptor
por: Osz, Judit, et al.
Publicado: (2015)

Structural basis for DNA recognition and allosteric control of the retinoic acid receptors RAR–RXR
por: Osz, Judit, et al.
Publicado: (2020)

Effects of electroacupuncture and the retinoid X receptor (RXR) signalling pathway on oligodendrocyte differentiation in the demyelinated spinal cord of rats
por: Yang, Xiao-Hua, et al.
Publicado: (2017)

Nuclear Hormone Retinoid X Receptor (RXR) Negatively Regulates the Glucose-Stimulated Insulin Secretion of Pancreatic β-Cells
por: Miyazaki, Satsuki, et al.
Publicado: (2010)

Gene Deregulation and Underlying Mechanisms in Spinocerebellar Ataxias With Polyglutamine Expansion
por: Niewiadomska-Cimicka, Anna, et al.
Publicado: (2020)

PML–RARA-RXR Oligomers Mediate Retinoid and Rexinoid/cAMP Cross-Talk in Acute Promyelocytic Leukemia Cell Differentiation
por: Kamashev, Dmitrii, et al.
Publicado: (2004)

P22. SELECTIVE ACTIVATION OF RETINOID-X-RECEPTOR (RXR) ACTIVATES PROLIFERATION AND MIGRATION OF PRIMARY HUMAN LYMPHATIC ENDOTHELIAL CELLS
por: Hsu, Jerry F., et al.
Publicado: (2022)

RAR/RXR binding dynamics distinguish pluripotency from differentiation associated cis-regulatory elements
por: Chatagnon, Amandine, et al.
Publicado: (2015)

RAR/RXR and PPAR/RXR Signaling in Spinal Cord Injury
por: van Neerven, Sabien, et al.
Publicado: (2007)

Regulation of RXR-RAR Heterodimers by RXR- and RAR-Specific Ligands and Their Combinations
por: le Maire, Albane, et al.
Publicado: (2019)

Abstract 108: 9-cis-Retinoic acid Reduces Postsurgical Lymphedema Through Rxrα Signaling Pathway
por: Sung, Cynthia, et al.
Publicado: (2019)

Ligand Dependent Switch from RXR Homo- to RXR-NURR1 Heterodimerization
por: Scheepstra, Marcel, et al.
Publicado: (2017)

1314. Defining Variability in the Evaluation and Management of Children with Chronic Osteomyelitis
por: Moorthy, Ganga S, et al.
Publicado: (2022)

An Isochroman Analog of CD3254 and Allyl-, Isochroman-Analogs of NEt-TMN Prove to Be More Potent Retinoid-X-Receptor (RXR) Selective Agonists Than Bexarotene
por: Jurutka, Peter W., et al.
Publicado: (2022)

Analysis of RXR/THR and RXR/PPARG2 Heterodimerization by Bioluminescence Resonance Energy Transfer (BRET)
por: Mulero, Miquel, et al.
Publicado: (2013)

A Familial Case of Robertsonian Translocation 13;14: Case Report
por: Saeed, Sondas, et al.
Publicado: (2022)

Sexually Dimorphic Genome-Wide Binding of Retinoid X Receptor alpha (RXRα) Determines Male-Female Differences in the Expression of Hepatic Lipid Processing Genes in Mice
por: Kosters, Astrid, et al.
Publicado: (2013)

Steroids from the Deep-Sea-Derived Fungus Penicillium granulatum MCCC 3A00475 Induced Apoptosis via Retinoid X Receptor (RXR)-α Pathway
por: Xie, Chun-Lan, et al.
Publicado: (2019)

Attenuation of Colon Inflammation through Activators of the Retinoid X Receptor (Rxr)/Peroxisome Proliferator–Activated Receptor γ (Pparγ) Heterodimer: A Basis for New Therapeutic Strategies
por: Desreumaux, Pierre, et al.
Publicado: (2001)

Correlation of Peroxisome Proliferator-Activated Receptor-γ (PPAR-γ) and Retinoid X Receptor-α (RXR-α) expression with clinical risk factors in patients with advanced carotid atherosclerosis
por: Giaginis, Constantinos, et al.
Publicado: (2011)

Allergen-Induced Dermatitis Causes Alterations in Cutaneous Retinoid-Mediated Signaling in Mice
por: Gericke, Janine, et al.
Publicado: (2013)

Vitamin D and Its Receptor from a Structural Perspective
por: Rochel, Natacha
Publicado: (2022)

Combination of Gonadal Dysgenesis and Monosomy X with a Novo Translocation (13,14)
por: Latrech, Hanane, et al.
Publicado: (2018)

1314. Missed Opportunities for Early Treatment and Prevention of Community Acquired Bacterial Meningitis
por: Beard, Glenn H, et al.
Publicado: (2023)

Comprehensive Set of Tertiary Complex Structures and Palmitic Acid Binding Provide Molecular Insights into Ligand Design for RXR Isoforms
por: Chaikuad, Apirat, et al.
Publicado: (2020)

Selective transduction of cerebellar Purkinje and granule neurons using delivery of AAV-PHP.eB and AAVrh10 vectors at axonal terminal locations
por: Surdyka, Magdalena, et al.
Publicado: (2022)

Changes in retinoid metabolism and signaling associated with metabolic remodeling during fasting and in type I diabetes
por: Klyuyeva, Alla V., et al.
Publicado: (2021)

1314. Neonatal Serum Gentamicin Concentrations following Maternal Once-daily Gentamicin Dosing
por: Wilson, Genene A, et al.
Publicado: (2020)

Structures, Biosynthesis, and Physiological Functions of (1,3;1,4)-β-d-Glucans
por: Chang, Shu-Chieh, et al.
Publicado: (2021)

P1314: MONITORING OF CIRCULATING CELL FREE DNA IN HEMATOPOIETIC STEM CELL DONORS
por: Rybolovleva, Tatyana, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ckpdoi61soh3f8vpgb9unuoehs