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Gag-Pol Transframe Domain p6* Is Essential for HIV-1 Protease-Mediated Virus Maturation
HIV-1 protease (PR) is encoded by pol, which is initially translated as a Pr160(gag-pol) polyprotein by a ribosomal frameshift event. Within Gag-Pol, truncated p6gag is replaced by a transframe domain (referred to as p6* or p6pol) located directly upstream of PR. p6* has been proposed as playing a r...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451514/ https://www.ncbi.nlm.nih.gov/pubmed/26030443 http://dx.doi.org/10.1371/journal.pone.0127974 |