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Molecular Dynamic Simulations Reveal the Structural Determinants of Fatty Acid Binding to Oxy-Myoglobin

The mechanism(s) by which fatty acids are sequestered and transported in muscle have not been fully elucidated. A potential key player in this process is the protein myoglobin (Mb). Indeed, there is a catalogue of empirical evidence supporting direct interaction of globins with fatty acid metabolite...

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Detalles Bibliográficos
Autores principales: Chintapalli, Sree V., Bhardwaj, Gaurav, Patel, Reema, Shah, Natasha, Patterson, Randen L., van Rossum, Damian B., Anishkin, Andriy, Adams, Sean H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451517/
https://www.ncbi.nlm.nih.gov/pubmed/26030763
http://dx.doi.org/10.1371/journal.pone.0128496