Analysis of deletion breakpoints from 1,092 humans reveals details of mutation mechanisms

Investigating genomic structural variants at basepair resolution is crucial for understanding their formation mechanisms. We identify and analyze 8,943 deletion breakpoints in 1,092 samples from the 1000 Genomes Project. We find breakpoints have more nearby SNPs and indels than the genomic average,...

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Detalles Bibliográficos
Autores principales: Abyzov, Alexej, Li, Shantao, Kim, Daniel Rhee, Mohiyuddin, Marghoob, Stütz, Adrian M., Parrish, Nicholas F., Mu, Xinmeng Jasmine, Clark, Wyatt, Chen, Ken, Hurles, Matthew, Korbel, Jan O., Lam, Hugo Y. K., Lee, Charles, Gerstein, Mark B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451611/
https://www.ncbi.nlm.nih.gov/pubmed/26028266
http://dx.doi.org/10.1038/ncomms8256

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451611/
https://www.ncbi.nlm.nih.gov/pubmed/26028266
http://dx.doi.org/10.1038/ncomms8256

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