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A negative feedback loop controls NMDA receptor function in cortical interneurons via neuregulin 2/ErbB4 signalling

The neuregulin receptor ErbB4 is an important modulator of GABAergic interneurons and neural network synchronization. However, little is known about the endogenous ligands that engage ErbB4, the neural processes that activate them or their direct downstream targets. Here we demonstrate, in cultured...

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Detalles Bibliográficos
Autores principales: Vullhorst, Detlef, Mitchell, Robert M., Keating, Carolyn, Roychowdhury, Swagata, Karavanova, Irina, Tao-Cheng, Jung-Hwa, Buonanno, Andres
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451617/
https://www.ncbi.nlm.nih.gov/pubmed/26027736
http://dx.doi.org/10.1038/ncomms8222