Cargando…

A negative feedback loop controls NMDA receptor function in cortical interneurons via neuregulin 2/ErbB4 signalling

The neuregulin receptor ErbB4 is an important modulator of GABAergic interneurons and neural network synchronization. However, little is known about the endogenous ligands that engage ErbB4, the neural processes that activate them or their direct downstream targets. Here we demonstrate, in cultured...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vullhorst, Detlef, Mitchell, Robert M., Keating, Carolyn, Roychowdhury, Swagata, Karavanova, Irina, Tao-Cheng, Jung-Hwa, Buonanno, Andres
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Pub. Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451617/ https://www.ncbi.nlm.nih.gov/pubmed/26027736 http://dx.doi.org/10.1038/ncomms8222

Ejemplares similares

ER-PM Junctions on GABAergic Interneurons Are Organized by Neuregulin 2/VAP Interactions and Regulated by NMDA Receptors
por: Vullhorst, Detlef, et al.
Publicado: (2023)

Transcytosis and trans-synaptic retention by postsynaptic ErbB4 underlie axonal accumulation of NRG3
por: Ahmad, Tanveer, et al.
Publicado: (2022)

Expression of the Neuregulin Receptor ErbB4 in the Brain of the Rhesus Monkey (Macaca mulatta)
por: Neddens, Jörg, et al.
Publicado: (2011)

ErbB4 signaling in dopaminergic axonal projections increases extracellular dopamine levels and regulates spatial/working memory behaviors
por: Skirzewski, M, et al.
Publicado: (2017)

Neuregulin repellent signaling via ErbB4 restricts GABAergic interneurons to migratory paths from ganglionic eminence to cortical destinations
por: Li, Hao, et al.
Publicado: (2012)

On the Modulatory Roles of Neuregulins/ErbB Signaling on Synaptic Plasticity
por: Ledonne, Ada, et al.
Publicado: (2019)

Clozapine-dependent inhibition of EGF/neuregulin receptor (ErbB) kinases
por: Kobayashi, Yutaro, et al.
Publicado: (2019)

Cdk5 Phosphorylation of ErbB4 is Required for Tangential Migration of Cortical Interneurons
por: Rakić, Sonja, et al.
Publicado: (2015)

Neuregulin-1-mediated ErbB2–ErbB3 signalling protects human trophoblasts against apoptosis to preserve differentiation
por: Fock, Valerie, et al.
Publicado: (2015)

Neuregulin/ErbB regulate neuromuscular junction development by phosphorylation of α-dystrobrevin
por: Schmidt, Nadine, et al.
Publicado: (2011)

Neuregulin-2 ablation results in dopamine dysregulation and severe behavioral phenotypes relevant to psychiatric disorders
por: Yan, L, et al.
Publicado: (2018)

Expression and Localization of Neuregulin-1 (Nrg1) and ErbB2/ErbB4 Receptors in Main Endocrine Organs of the Rhesus Monkey
por: Zhao, Wei-jiang
Publicado: (2013)

Characterization of Glial Cell Models and In Vitro Manipulation of the Neuregulin1/ErbB System
por: Pascal, Davide, et al.
Publicado: (2014)

Modulation of the Neuregulin 1/ErbB system after skeletal muscle denervation and reinnervation
por: Morano, Michela, et al.
Publicado: (2018)

Dysregulation of Neuregulin-1/ErbB signaling in the hippocampus of rats after administration of doxorubicin
por: Liao, Dehua, et al.
Publicado: (2018)

ErbB2 Dephosphorylation and Anti-Proliferative Effects of Neuregulin-1 in ErbB2-Overexpressing Cells; Re-evaluation of Their Low-Affinity Interaction
por: Wang, Ran, et al.
Publicado: (2013)

Neuregulin1/ErbB4-induced migration in ST14A striatal progenitors: calcium-dependent mechanisms and modulation by NMDA receptor activation
por: Pregno, Giulia, et al.
Publicado: (2011)

Neuregulin-1/ErbB4 signaling modulates Plasmodium falciparum HRP2-induced damage to brain cortical organoids
por: Harbuzariu, Adriana, et al.
Publicado: (2022)

Interactions among genes in the ErbB-Neuregulin signalling network are associated with increased susceptibility to schizophrenia
por: Benzel, Isabel, et al.
Publicado: (2007)

Activation of Neuregulin 1/ErbB Signaling Is Involved in the Development of TOCP-Induced Delayed Neuropathy
por: Xu, Hai-Yang, et al.
Publicado: (2018)

Neuregulin 1/ErbB4 signaling contributes to the anti-epileptic effects of the ketogenic diet
por: Wang, Jin, et al.
Publicado: (2021)

Neuregulin 1 Type III/ErbB Signaling Is Crucial for Schwann Cell Colonization of Sympathetic Axons
por: Heermann, Stephan, et al.
Publicado: (2011)

The immunoglobulin‐like domain of neuregulins potentiates ErbB3/HER3 activation and cellular proliferation
por: Centa, Ariana, et al.
Publicado: (2018)

Author Correction: Modulation of the Neuregulin 1/ErbB system after skeletal muscle denervation and reinnervation
por: Morano, Michela, et al.
Publicado: (2020)

Neuregulin1-ErbB4 Signaling in Spinal Cord Participates in Electroacupuncture Analgesia in Inflammatory Pain
por: Wan, Chaofan, et al.
Publicado: (2021)

Alteration in Neuregulin 1/ERbB4 in Absence Epilepsy: Regulatory Effect on TRPV1 Expression
por: Talebi, Farideh, et al.
Publicado: (2022)

Overexpression of neuregulin 1 in GABAergic interneurons results in reversible cortical disinhibition
por: Wang, Yao-Yi, et al.
Publicado: (2021)

Acute doxorubicin cardiotoxicity is associated with miR-146a-induced inhibition of the neuregulin-ErbB pathway
por: Horie, Takahiro, et al.
Publicado: (2010)

Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids
por: Jardé, Thierry, et al.
Publicado: (2016)

Disrupted hippocampal neuregulin-1/ErbB3 signaling and dentate gyrus granule cell alterations in suicide
por: Mahar, I, et al.
Publicado: (2017)

Disrupted hippocampal neuregulin-1/ErbB3 signaling and dentate gyrus granule cell alterations in suicide
por: Mahar, I, et al.
Publicado: (2017)

Neuregulin 3 Mediates Cortical Plate Invasion and Laminar Allocation of GABAergic Interneurons
por: Bartolini, Giorgia, et al.
Publicado: (2017)

Activation of an early feedback survival loop involving phospho-ErbB3 is a general response of melanoma cells to RAF/MEK inhibition and is abrogated by anti-ErbB3 antibodies
por: Fattore, Luigi, et al.
Publicado: (2013)

Presynaptic Type III Neuregulin1-ErbB signaling targets α7 nicotinic acetylcholine receptors to axons
por: Hancock, Melissa L., et al.
Publicado: (2008)

Increased Expression of Neuregulin 1 and erbB2 Tyrosine Kinase in the Bladder of Rats With Cyclophosphamide-Induced Interstitial Cystitis
por: Song, Ki Hak, et al.
Publicado: (2015)

Ablation of neuropsin–neuregulin 1 signaling imbalances ErbB4 inhibitory networks and disrupts hippocampal gamma oscillation
por: Kawata, M, et al.
Publicado: (2017)

Modulation of ErbB2 Blockade in ErbB2-Positive Cancers: The Role of ErbB2 Mutations and PHLDA1
por: Li, Guangyuan, et al.
Publicado: (2014)

Epistatic and Functional Interactions of Catechol-O-Methyltransferase (COMT) and AKT1 on Neuregulin1-ErbB Signaling in Cell Models
por: Sei, Yoshitatsu, et al.
Publicado: (2010)

L1CAM Binds ErbB Receptors through Ig-Like Domains Coupling Cell Adhesion and Neuregulin Signalling
por: Donier, Emanuelle, et al.
Publicado: (2012)

Neuregulin Facilitates Nerve Regeneration by Speeding Schwann Cell Migration via ErbB2/3-Dependent FAK Pathway
por: Chang, Hung-Ming, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_viiqv52nqei2i9fee22122qvpb