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Evaluating the potential of polymer nanoparticles for oral delivery of paclitaxel in drug-resistant cancer

The present study was designed to explore the ability of polymeric nanoparticles to restore drug sensitivity to P-glycoprotein over-expressing cancer cells. A multidrug-resistant cell line 2780 AD and its sensitive parent cell line A2780 were studied in cell culture and as a xenografted tumour model...

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Detalles Bibliográficos
Autores principales: Bhardwaj, V., Plumb, J. A., Cassidy, J., Ravi Kumar, M. N. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451632/
https://www.ncbi.nlm.nih.gov/pubmed/26069477
http://dx.doi.org/10.1007/s12645-010-0004-2