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Boosted Influenza-Specific T Cell Responses after H5N1 Pandemic Live Attenuated Influenza Virus Vaccination

BACKGROUND: In a phase I clinical trial, a H5N1 pandemic live attenuated influenza virus (pLAIV) VN2004 vaccine bearing avian influenza H5N1 hemagglutinin (HA) and NA genes on the A/Ann Arbor cold-adapted vaccine backbone displayed very restricted replication. We evaluated T cell responses to H5N1 p...

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Detalles Bibliográficos
Autores principales: Peng, YanChun, Wang, Beibei, Talaat, Kawsar, Karron, Ruth, Powell, Timothy J., Zeng, Hui, Dong, Danning, Luke, Catherine J., McMichael, Andrew, Subbarao, Kanta, Dong, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451682/
https://www.ncbi.nlm.nih.gov/pubmed/26082783
http://dx.doi.org/10.3389/fimmu.2015.00287