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Decoupling the role of stiffness from other hydroxyapatite signalling cues in periosteal derived stem cell differentiation

Bone extracellular matrix (ECM) is a natural composite made of collagen and mineral hydroxyapatite (HA). Dynamic cell-ECM interactions play a critical role in regulating cell differentiation and function. Understanding the principal ECM cues promoting osteogenic differentiation would be pivotal for...

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Detalles Bibliográficos
Autores principales: Mattei, Giorgio, Ferretti, Concetta, Tirella, Annalisa, Ahluwalia, Arti, Mattioli-Belmonte, Monica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451686/
https://www.ncbi.nlm.nih.gov/pubmed/26035412
http://dx.doi.org/10.1038/srep10778