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Modulation of extracellular matrix in cancer is associated with enhanced tumor cell targeting by bacteriophage vectors

BACKGROUND: Gene therapy has been an attractive paradigm for cancer treatment. However, cancer gene therapy has been challenged by the inherent limitation of vectors that are able to deliver therapeutic genes to tumors specifically and efficiently following systemic administration. Bacteriophage (ph...

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Detalles Bibliográficos
Autores principales: Yata, Teerapong, Lee, Eugene L. Q., Suwan, Keittisak, Syed, Nelofer, Asavarut, Paladd, Hajitou, Amin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451735/
https://www.ncbi.nlm.nih.gov/pubmed/26037383
http://dx.doi.org/10.1186/s12943-015-0383-4