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Modulation of extracellular matrix in cancer is associated with enhanced tumor cell targeting by bacteriophage vectors
BACKGROUND: Gene therapy has been an attractive paradigm for cancer treatment. However, cancer gene therapy has been challenged by the inherent limitation of vectors that are able to deliver therapeutic genes to tumors specifically and efficiently following systemic administration. Bacteriophage (ph...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451735/ https://www.ncbi.nlm.nih.gov/pubmed/26037383 http://dx.doi.org/10.1186/s12943-015-0383-4 |