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Pannexin1 channels dominate ATP release in the cochlea ensuring endocochlear potential and auditory receptor potential generation and hearing

Pannexin1 (Panx1) is a gap junction gene in vertebrates whose proteins mainly function as non-junctional channels on the cell surface. Panx1 channels can release ATP under physiological conditions and play critical roles in many physiological and pathological processes. Here, we report that Panx1 de...

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Detalles Bibliográficos
Autores principales: Chen, Jin, Zhu, Yan, Liang, Chun, Chen, Jing, Zhao, Hong-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451810/
https://www.ncbi.nlm.nih.gov/pubmed/26035172
http://dx.doi.org/10.1038/srep10762