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Pannexin1 channels dominate ATP release in the cochlea ensuring endocochlear potential and auditory receptor potential generation and hearing
Pannexin1 (Panx1) is a gap junction gene in vertebrates whose proteins mainly function as non-junctional channels on the cell surface. Panx1 channels can release ATP under physiological conditions and play critical roles in many physiological and pathological processes. Here, we report that Panx1 de...
Autores principales: | Chen, Jin, Zhu, Yan, Liang, Chun, Chen, Jing, Zhao, Hong-Bo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451810/ https://www.ncbi.nlm.nih.gov/pubmed/26035172 http://dx.doi.org/10.1038/srep10762 |
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