Sulforaphane attenuates EGFR signaling in NSCLC cells

BACKGROUND: EGFR, a receptor tyrosine kinase (RTK), is frequently overexpressed and mutated in non-small cell lung cancer (NSCLC). Tyrosine kinase inhibitors (TKIs) have been widely used in the treatment of many cancers, including NSCLC. However, intrinsic and acquired resistance to TKI remains a co...

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Detalles Bibliográficos
Autores principales: Chen, Chi-Yuan, Yu, Zhu-Yun, Chuang, Yen-Shu, Huang, Rui-Mei, Wang, Tzu-Chien V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451877/
https://www.ncbi.nlm.nih.gov/pubmed/26036303
http://dx.doi.org/10.1186/s12929-015-0139-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451877/
https://www.ncbi.nlm.nih.gov/pubmed/26036303
http://dx.doi.org/10.1186/s12929-015-0139-x

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