Functional display of heterotetrameric human protein kinase CK2 on Escherichia coli: a novel tool for drug discovery

BACKGROUND: Human protein kinase CK2 represents a novel therapeutic target for neoplastic diseases. Inhibitors are in need to explore the druggability and the therapeutic options of this enzyme. A bottleneck in the search for new inhibitors is the availability of the target for testing. Therefore an...

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Detalles Bibliográficos
Autores principales: Gratz, Andreas, Bollacke, Andre, Stephan, Sara, Nienberg, Christian, Le Borgne, Marc, Götz, Claudia, Jose, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451881/
https://www.ncbi.nlm.nih.gov/pubmed/26036951
http://dx.doi.org/10.1186/s12934-015-0263-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451881/
https://www.ncbi.nlm.nih.gov/pubmed/26036951
http://dx.doi.org/10.1186/s12934-015-0263-z

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