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Functional display of heterotetrameric human protein kinase CK2 on Escherichia coli: a novel tool for drug discovery

BACKGROUND: Human protein kinase CK2 represents a novel therapeutic target for neoplastic diseases. Inhibitors are in need to explore the druggability and the therapeutic options of this enzyme. A bottleneck in the search for new inhibitors is the availability of the target for testing. Therefore an...

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Detalles Bibliográficos
Autores principales:	Gratz, Andreas, Bollacke, Andre, Stephan, Sara, Nienberg, Christian, Le Borgne, Marc, Götz, Claudia, Jose, Joachim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451881/ https://www.ncbi.nlm.nih.gov/pubmed/26036951 http://dx.doi.org/10.1186/s12934-015-0263-z

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