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Genome-wide analysis of primary peripheral blood mononuclear cells from HIV + patients-pre-and post- HAART show immune activation and inflammation the main drivers of host gene expression

BACKGROUND: Although the host gene expression in the context of HIV has been explored by several studies, it remains unclear how HIV is able to manipulate and subvert host gene machinery before and after highly active antiretroviral therapy (HAART) in the same individual. In order to define the unde...

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Detalles Bibliográficos
Autores principales: da Conceicao, Viviane N, Dyer, Wayne B, Gandhi, Kaushal, Gupta, Priyanka, Saksena, Nitin K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451969/
https://www.ncbi.nlm.nih.gov/pubmed/26056580
http://dx.doi.org/10.1186/2052-8426-2-11