EILDV-conjugated, etoposide-loaded biodegradable polymeric micelles directing to tumor metastatic cells overexpressing α4β1 integrin

In the present study, poly(ethylene glycol)-b-poly(ε-caprolactone) micelles loaded with etoposide (ETO) were formulated and further conjugated with pentapeptide Glu-Ile-Leu-Asp-Val (EILDV) to target α4β1 integrin receptor overexpressed on metastatic tumor cell. Using a distinct ratio of carboxyl-ter...

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Detalles Bibliográficos
Autores principales: Ukawala, Mukesh, Rajyaguru, Tushar, Chaudhari, Kiran, Manjappa, A. S., Murthy, R. S. R., Gude, Rajiv
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2011
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451974/
https://www.ncbi.nlm.nih.gov/pubmed/26069491
http://dx.doi.org/10.1007/s12645-011-0023-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4451974/
https://www.ncbi.nlm.nih.gov/pubmed/26069491
http://dx.doi.org/10.1007/s12645-011-0023-7

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