A critical evaluation of PI3K inhibition in Glioblastoma and Neuroblastoma therapy

Members of the PI3K/Akt/mTor signaling cascade are among the most frequently altered proteins in cancer, yet the therapeutic application of pharmacological inhibitors of this signaling network, either as monotherapy or in combination therapy (CT) has so far not been particularly successful. In this...

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Detalles Bibliográficos
Autores principales: Westhoff, Mike-Andrew, Karpel-Massler, Georg, Brühl, Oliver, Enzenmüller, Stefanie, La Ferla-Brühl, Katia, Siegelin, Markus D, Nonnenmacher, Lisa, Debatin, Klaus-Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452069/
https://www.ncbi.nlm.nih.gov/pubmed/26056598
http://dx.doi.org/10.1186/2052-8426-2-32

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452069/
https://www.ncbi.nlm.nih.gov/pubmed/26056598
http://dx.doi.org/10.1186/2052-8426-2-32

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