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Gemcitabine-loaded PLGA-PEG immunonanoparticles for targeted chemotherapy of pancreatic cancer

The aim of the present study was the direct covalent coupling of the epidermal growth factor receptor (EGFR)-specific monoclonal antibody (mAb) to the surface of poly(lactide)-co-glycolide (PLGA)-polyethylene glycol (PEG) nanoparticles in order to achieve a cell type-specific drug carrier system aga...

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Detalles Bibliográficos
Autores principales: Aggarwal, Sahil, Gupta, Swati, Pabla, Dilrose, Murthy, R. S. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452077/
https://www.ncbi.nlm.nih.gov/pubmed/26069510
http://dx.doi.org/10.1007/s12645-013-0046-3