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The HSP90 inhibitor ganetespib: A potential effective agent for Acute Myeloid Leukemia in combination with cytarabine

HSP90 is a multi-client chaperone involved in regulating a large array of cellular processes and is commonly overexpressed in many different cancer types including hematological malignancies. Inhibition of HSP90 holds promise for targeting multiple molecular abnormalities and is therefore an attract...

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Detalles Bibliográficos
Autores principales: Lazenby, M., Hills, R., Burnett, A.K., Zabkiewicz, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452084/
https://www.ncbi.nlm.nih.gov/pubmed/25882550
http://dx.doi.org/10.1016/j.leukres.2015.03.016