Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy

Neuropathic pain treatment remains a challenge because pathomechanism is not fully understood. It is believed that glial activation and increased spinal nociceptive factors are crucial for neuropathy. We investigated the effect of parthenolide (PTL) on the chronic constriction injury to the sciatic...

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Detalles Bibliográficos
Autores principales: Popiolek-Barczyk, Katarzyna, Kolosowska, Natalia, Piotrowska, Anna, Makuch, Wioletta, Rojewska, Ewelina, Jurga, Agnieszka M., Pilat, Dominika, Mika, Joanna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452088/
https://www.ncbi.nlm.nih.gov/pubmed/26090236
http://dx.doi.org/10.1155/2015/676473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452088/
https://www.ncbi.nlm.nih.gov/pubmed/26090236
http://dx.doi.org/10.1155/2015/676473

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