Cargando…
Parthenolide Relieves Pain and Promotes M2 Microglia/Macrophage Polarization in Rat Model of Neuropathy
Neuropathic pain treatment remains a challenge because pathomechanism is not fully understood. It is believed that glial activation and increased spinal nociceptive factors are crucial for neuropathy. We investigated the effect of parthenolide (PTL) on the chronic constriction injury to the sciatic...
Autores principales: | Popiolek-Barczyk, Katarzyna, Kolosowska, Natalia, Piotrowska, Anna, Makuch, Wioletta, Rojewska, Ewelina, Jurga, Agnieszka M., Pilat, Dominika, Mika, Joanna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452088/ https://www.ncbi.nlm.nih.gov/pubmed/26090236 http://dx.doi.org/10.1155/2015/676473 |
Ejemplares similares
-
PD98059 Influences Immune Factors and Enhances Opioid Analgesia in Model of Neuropathy
por: Rojewska, Ewelina, et al.
Publicado: (2015) -
Blockade of Toll-Like Receptors (TLR2, TLR4) Attenuates Pain and Potentiates Buprenorphine Analgesia in a Rat Neuropathic Pain Model
por: Jurga, Agnieszka M., et al.
Publicado: (2016) -
Minocycline Enhances the Effectiveness of Nociceptin/Orphanin FQ during Neuropathic Pain
por: Popiolek-Barczyk, Katarzyna, et al.
Publicado: (2014) -
Delta-Opioid Receptor Analgesia Is Independent of Microglial Activation in a Rat Model of Neuropathic Pain
por: Mika, Joanna, et al.
Publicado: (2014) -
Botulinum Toxin Type A—A Modulator of Spinal Neuron–Glia Interactions under Neuropathic Pain Conditions
por: Rojewska, Ewelina, et al.
Publicado: (2018)