Autophagy-Regulated ROS from Xanthine Oxidase Acts as an Early Effector for Triggering Late Mitochondria-Dependent Apoptosis in Cathepsin S-Targeted Tumor Cells

Cathepsin S (CTSS), which is highly expressed in various malignant tumor cells, has been proposed to promote tumor progression, migration, and invasion. CTSS inhibition not only blocks tumor cell invasion and endothelial tube formation but also induces cellular cytotoxicity. In our previous studies,...

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Detalles Bibliográficos
Autores principales: Huang, Chien-Chang, Lee, Cheng-Che, Lin, Hsiao-Han, Chen, Mei-Chi, Lin, Chun-Cheng, Chang, Jang-Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452096/
https://www.ncbi.nlm.nih.gov/pubmed/26029922
http://dx.doi.org/10.1371/journal.pone.0128045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452096/
https://www.ncbi.nlm.nih.gov/pubmed/26029922
http://dx.doi.org/10.1371/journal.pone.0128045

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