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WNT/β-Catenin Signaling Is Required for Integration of CD(24+) Renal Progenitor Cells into Glycerol-Damaged Adult Renal Tubules

During development, nephron progenitor cells (NPC) are induced to differentiate by WNT9b signals from the ureteric bud. Although nephrogenesis ends in the perinatal period, acute kidney injury (AKI) elicits repopulation of damaged nephrons. Interestingly, embryonic NPC infused into adult mice with A...

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Detalles Bibliográficos
Autores principales: Zhang, Zhao, Iglesias, Diana M., Corsini, Rachel, Chu, LeeLee, Goodyer, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452100/
https://www.ncbi.nlm.nih.gov/pubmed/26089915
http://dx.doi.org/10.1155/2015/391043