Validation study of the combined repeated-dose toxicity and genotoxicity assay using gpt delta rats

Transgenic rodents carrying reporter genes to detect organ-specific in vivo genetic alterations are useful for risk assessment of genotoxicity that causes cancer. Thus, the Organization for Economic Co-operation and Development has established the guideline for genotoxicity tests using transgenic an...

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Detalles Bibliográficos
Autores principales: Akagi, Jun-ichi, Toyoda, Takeshi, Cho, Young-Man, Mizuta, Yasuko, Nohmi, Takehiko, Nishikawa, Akiyoshi, Ogawa, Kumiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452153/
https://www.ncbi.nlm.nih.gov/pubmed/25683344
http://dx.doi.org/10.1111/cas.12634

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452153/
https://www.ncbi.nlm.nih.gov/pubmed/25683344
http://dx.doi.org/10.1111/cas.12634

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