Sirtuin 6 promotes transforming growth factor-β1/H(2)O(2)/HOCl-mediated enhancement of hepatocellular carcinoma cell tumorigenicity by suppressing cellular senescence

Sirtuin 6 (SIRT6) can function as a tumor suppressor by suppressing aerobic glycolysis and apoptosis resistance. However, the negative effect of SIRT6 on cellular senescence implies that it may also have the potential to promote tumor development. Here we report that the upregulation of SIRT6 expres...

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Detalles Bibliográficos
Autores principales: Feng, Xin-Xia, Luo, Jing, Liu, Mei, Yan, Wei, Zhou, Zhen-Zhen, Xia, Yu-Jia, Tu, Wei, Li, Pei-Yuan, Feng, Zuo-Hua, Tian, De-An
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452156/
https://www.ncbi.nlm.nih.gov/pubmed/25683165
http://dx.doi.org/10.1111/cas.12632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452156/
https://www.ncbi.nlm.nih.gov/pubmed/25683165
http://dx.doi.org/10.1111/cas.12632

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