Theoretical Insights Reveal Novel Motions in Csk’s SH3 Domain That Control Kinase Activation

The Src family of tyrosine kinases (SFKs) regulate numerous aspects of cell growth and differentiation and are under the principal control of the C-terminal Src Kinase (Csk). Although Csk and SFKs share conserved kinase, SH2 and SH3 domains, they differ considerably in three-dimensional structure, r...

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Detalles Bibliográficos
Autores principales: Barkho, Sulyman, Pierce, Levi C. T., Li, Sheng, Adams, Joseph A., Jennings, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452171/
https://www.ncbi.nlm.nih.gov/pubmed/26030592
http://dx.doi.org/10.1371/journal.pone.0127724

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452171/
https://www.ncbi.nlm.nih.gov/pubmed/26030592
http://dx.doi.org/10.1371/journal.pone.0127724

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