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Theoretical Insights Reveal Novel Motions in Csk’s SH3 Domain That Control Kinase Activation
The Src family of tyrosine kinases (SFKs) regulate numerous aspects of cell growth and differentiation and are under the principal control of the C-terminal Src Kinase (Csk). Although Csk and SFKs share conserved kinase, SH2 and SH3 domains, they differ considerably in three-dimensional structure, r...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452171/ https://www.ncbi.nlm.nih.gov/pubmed/26030592 http://dx.doi.org/10.1371/journal.pone.0127724 |