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Histidine Decarboxylase Deficiency Prevents Autoimmune Diabetes in NOD Mice

Recent evidence has highlighted the role of histamine in inflammation. Since this monoamine has also been strongly implicated in the pathogenesis of type-1 diabetes, we assessed its effect in the nonobese diabetic (NOD) mouse model. To this end, we used mice (inactivated) knocked out for the gene en...

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Detalles Bibliográficos
Autores principales: Alkan, Manal, Machavoine, François, Rignault, Rachel, Dam, Julie, Dy, Michel, Thieblemont, Nathalie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452174/
https://www.ncbi.nlm.nih.gov/pubmed/26090474
http://dx.doi.org/10.1155/2015/965056