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Histidine Decarboxylase Deficiency Prevents Autoimmune Diabetes in NOD Mice
Recent evidence has highlighted the role of histamine in inflammation. Since this monoamine has also been strongly implicated in the pathogenesis of type-1 diabetes, we assessed its effect in the nonobese diabetic (NOD) mouse model. To this end, we used mice (inactivated) knocked out for the gene en...
Autores principales: | Alkan, Manal, Machavoine, François, Rignault, Rachel, Dam, Julie, Dy, Michel, Thieblemont, Nathalie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452174/ https://www.ncbi.nlm.nih.gov/pubmed/26090474 http://dx.doi.org/10.1155/2015/965056 |
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