Polymorphisms in Autophagy Genes Are Associated with Paget Disease of Bone

Paget disease of bone (PDB) is a focal bone disorder affecting the skeleton segmentally. The main alteration resides in osteoclasts that increase in size, number and activity. Many osteoclasts have cytoplasmic inclusions that have been associated with protein aggregates, increasing the evidences of...

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Detalles Bibliográficos
Autores principales: Usategui-Martín, Ricardo, García-Aparicio, Judith, Corral-Gudino, Luis, Calero-Paniagua, Ismael, Del Pino-Montes, Javier, González Sarmiento, Rogelio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452234/
https://www.ncbi.nlm.nih.gov/pubmed/26030385
http://dx.doi.org/10.1371/journal.pone.0128984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452234/
https://www.ncbi.nlm.nih.gov/pubmed/26030385
http://dx.doi.org/10.1371/journal.pone.0128984

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