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Exploring Treatment by Covariate Interactions Using Subgroup Analysis and Meta-Regression in Cochrane Reviews: A Review of Recent Practice

BACKGROUND: Treatment by covariate interactions can be explored in reviews using interaction analyses (e.g., subgroup analysis). Such analyses can provide information on how the covariate modifies the treatment effect and is an important methodological approach for personalising medicine. Guidance e...

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Detalles Bibliográficos
Autores principales: Donegan, Sarah, Williams, Lisa, Dias, Sofia, Tudur-Smith, Catrin, Welton, Nicky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452239/
https://www.ncbi.nlm.nih.gov/pubmed/26029923
http://dx.doi.org/10.1371/journal.pone.0128804