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Isolation and Characterization of Acetylated Derivative of Recombinant Insulin Lispro Produced in Escherichia coli

PURPOSE: Insulin lispro is a rapid-acting insulin analogue produced by recombinant DNA technology. As a biosynthetic drug, the protein undergoes strict monitoring aiming for detection and characterization of impurities. The goal of this study was to isolate and identify a derivative of insulin lispr...

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Detalles Bibliográficos
Autores principales: Szewczak, Joanna, Bierczyńska-Krzysik, Anna, Piejko, Marcin, Mak, Paweł, Stadnik, Dorota
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452257/
https://www.ncbi.nlm.nih.gov/pubmed/25663326
http://dx.doi.org/10.1007/s11095-015-1637-y