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Loss of SOX9 Expression Is Associated with PSA Recurrence in ERG-Positive and PTEN Deleted Prostate Cancers

The transcription factor SOX9 plays a crucial role in normal prostate development and has been suggested to drive prostate carcinogenesis in concert with PTEN inactivation. To evaluate the clinical impact of SOX9 and its relationship with key genomic alterations in prostate cancer, SOX9 expression w...

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Detalles Bibliográficos
Autores principales: Burdelski, Christoph, Bujupi, Erzen, Tsourlakis, Maria Christina, Hube-Magg, Claudia, Kluth, Martina, Melling, Nathaniel, Lebok, Patrick, Minner, Sarah, Koop, Christina, Graefen, Markus, Heinzer, Hans, Wittmer, Corinna, Sauter, Guido, Wilczak, Waldemar, Simon, Ronald, Schlomm, Thorsten, Steurer, Stefan, Krech, Till
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452277/
https://www.ncbi.nlm.nih.gov/pubmed/26030748
http://dx.doi.org/10.1371/journal.pone.0128525