Loss of RhoA Exacerbates, Rather Than Dampens, Oncogenic K-Ras Induced Lung Adenoma Formation in Mice

Numerous cellular studies have indicated that RhoA signaling is required for oncogenic Ras-induced transformation, suggesting that RhoA is a useful target in Ras induced neoplasia. However, to date very limited data exist to genetically attribute RhoA function to Ras-mediated tumorigenesis in mammal...

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Detalles Bibliográficos
Autores principales: Zandvakili, Inuk, Davis, Ashley Kuenzi, Hu, Guodong, Zheng, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452309/
https://www.ncbi.nlm.nih.gov/pubmed/26030593
http://dx.doi.org/10.1371/journal.pone.0127923

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452309/
https://www.ncbi.nlm.nih.gov/pubmed/26030593
http://dx.doi.org/10.1371/journal.pone.0127923

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