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Amino Acid Substitutions Improve the Immunogenicity of H7N7HA Protein and Protect Mice against Lethal H7N7 Viral Challenge

Avian influenza A H7N7/NL/219/03 virus creates a serious pandemic threat to human health because it can transmit directly from domestic poultry to humans and from human to human. Our previous vaccine study reported that mice when immunized intranasally (i.n) with live Bac-HA were protected from leth...

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Detalles Bibliográficos
Autores principales: kumar, Subaschandrabose Rajesh, Prabakaran, Mookkan, Ashok raj, Kattur Venkatachalam, He, Fang, Kwang, Jimmy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452345/
https://www.ncbi.nlm.nih.gov/pubmed/26030920
http://dx.doi.org/10.1371/journal.pone.0128940