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Induction of Apoptosis Coupled to Endoplasmic Reticulum Stress through Regulation of CHOP and JNK in Bone Marrow Mesenchymal Stem Cells from Patients with Systemic Lupus Erythematosus

Previous studies indicated that bone marrow mesenchymal stem cells (BM-MSCs) from patients with systemic lupus erythematosus (SLE) exhibited the phenomenon of apoptosis. In this study, we aimed to investigate whether apoptosis of BM-MSCs from SLE patients were dysregulated. In this paper, endoplasmi...

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Detalles Bibliográficos
Autores principales: Guo, Genkai, Meng, Yan, Tan, Wei, Xia, Yunfei, Cheng, Chun, Chen, Xiaolan, Gu, Zhifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452351/
https://www.ncbi.nlm.nih.gov/pubmed/26090483
http://dx.doi.org/10.1155/2015/183738