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Impaired Fracture Healing Caused by Deficiency of the Immunoreceptor Adaptor Protein DAP12
Osteoclasts play an important role in bone metabolism, but their exact role in fracture healing remains unclear. DAP12 is an immunoadaptor protein with associated immunoreceptors on myeloid lineage cells, including osteoclasts. Its deficiency causes osteopetrosis due to suppression of osteoclast dev...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452492/ https://www.ncbi.nlm.nih.gov/pubmed/26030755 http://dx.doi.org/10.1371/journal.pone.0128210 |