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Noise-Driven Causal Inference in Biomolecular Networks

Single-cell RNA and protein concentrations dynamically fluctuate because of stochastic ("noisy") regulation. Consequently, biological signaling and genetic networks not only translate stimuli with functional response but also random fluctuations. Intuitively, this feature manifests as the...

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Detalles Bibliográficos
Autores principales: Prill, Robert J., Vogel, Robert, Cecchi, Guillermo A., Altan-Bonnet, Grégoire, Stolovitzky, Gustavo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452541/
https://www.ncbi.nlm.nih.gov/pubmed/26030907
http://dx.doi.org/10.1371/journal.pone.0125777