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ATMIN Is Required for Maintenance of Genomic Stability and Suppression of B Cell Lymphoma

Defective V(D)J rearrangement of immunoglobulin heavy or light chain (IgH or IgL) or class switch recombination (CSR) can initiate chromosomal translocations. The DNA-damage kinase ATM is required for the suppression of chromosomal translocations but ATM regulation is incompletely understood. Here,...

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Detalles Bibliográficos
Autores principales: Loizou, Joanna I., Sancho, Rocio, Kanu, Nnennaya, Bolland, Daniel J., Yang, Fengtang, Rada, Cristina, Corcoran, Anne E., Behrens, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452547/
https://www.ncbi.nlm.nih.gov/pubmed/21575860
http://dx.doi.org/10.1016/j.ccr.2011.03.022