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Preclinical imaging of kallikrein-related peptidase 2 (hK2) in prostate cancer with a (111)In-radiolabelled monoclonal antibody, 11B6

BACKGROUND: Prostate cancer is a leading cause of death in the male population of the western world. Human kallikrein-related peptidase 2 (hK2) is abundantly expressed in malignant prostatic tissue, and its gene, KLK2, is regulated by the androgen receptor. 11B6 is a murine IgG(1) monoclonal antibod...

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Detalles Bibliográficos
Autores principales: Timmermand, Oskar Vilhelmsson, Ulmert, David, Evans-Axelsson, Susan, Pettersson, Kim, Bjartell, Anders, Lilja, Hans, Strand, Sven-Erik, Tran, Thuy A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452661/
https://www.ncbi.nlm.nih.gov/pubmed/26116115
http://dx.doi.org/10.1186/s13550-014-0051-5