Cargando…
Preclinical imaging of kallikrein-related peptidase 2 (hK2) in prostate cancer with a (111)In-radiolabelled monoclonal antibody, 11B6
BACKGROUND: Prostate cancer is a leading cause of death in the male population of the western world. Human kallikrein-related peptidase 2 (hK2) is abundantly expressed in malignant prostatic tissue, and its gene, KLK2, is regulated by the androgen receptor. 11B6 is a murine IgG(1) monoclonal antibod...
Autores principales: | Timmermand, Oskar Vilhelmsson, Ulmert, David, Evans-Axelsson, Susan, Pettersson, Kim, Bjartell, Anders, Lilja, Hans, Strand, Sven-Erik, Tran, Thuy A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452661/ https://www.ncbi.nlm.nih.gov/pubmed/26116115 http://dx.doi.org/10.1186/s13550-014-0051-5 |
Ejemplares similares
-
Radioimmunotherapy of prostate cancer targeting human kallikrein-related peptidase 2
por: Vilhelmsson Timmermand, O., et al.
Publicado: (2016) -
Preclinical efficacy of hK2 targeted [(177)Lu]hu11B6 for prostate cancer theranostics
por: Timmermand, Oskar Vilhelmsson, et al.
Publicado: (2019) -
Humanization, Radiolabeling and Biodistribution Studies of an IgG(1)-Type Antibody Targeting Uncomplexed PSA for Theranostic Applications
por: Strand, Joanna, et al.
Publicado: (2021) -
Small-scale dosimetry for alpha particle (241)Am source cell irradiation and estimation of γ-H2AX foci distribution in prostate cancer cell line PC3
por: Mellhammar, Emma, et al.
Publicado: (2022) -
Copy Number Variants in the Kallikrein Gene Cluster
por: Lindahl, Pernilla, et al.
Publicado: (2013)