Therapeutic application of CCK2R-targeting PP-F11: influence of particle range, activity and peptide amount

BACKGROUND: Targeted radionuclide therapy with high-energy beta-emitters is generally considered suboptimal to cure small tumours (<300 mg). Tumour targeting of the CCK2 receptor-binding minigastrin analogue PP-F11 was determined in a tumour-bearing mouse model at increasing peptide amounts. The...

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Detalles Bibliográficos
Autores principales: Konijnenberg, Mark W, Breeman, Wout A P, de Blois, Erik, Chan, Ho Sze, Boerman, Otto C, Laverman, Peter, Kolenc-Peitl, Petra, Melis, Marleen, de Jong, Marion
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452684/
https://www.ncbi.nlm.nih.gov/pubmed/26116111
http://dx.doi.org/10.1186/s13550-014-0047-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452684/
https://www.ncbi.nlm.nih.gov/pubmed/26116111
http://dx.doi.org/10.1186/s13550-014-0047-1

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