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Evaluation of retinol binding protein 4 and carbamoylated haemoglobin as potential renal toxicity biomarkers in adult mice treated with (177)Lu-octreotate

BACKGROUND: The kidneys are regarded as one of the main dose-limiting organs in the treatment of neuroendocrine tumours with (177)Lu-[DOTA(0), Tyr(3)]-octreotate ((177)Lu-octreotate), despite the successful use of kidney uptake blocking agents such as lysine and arginine. To avoid renal toxicity but...

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Detalles Bibliográficos
Autores principales: Dalmo, Johanna, Westberg, Emelie, Barregard, Lars, Svedbom, Lisa, Johansson, Martin, Törnqvist, Margareta, Forssell-Aronsson, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452688/
https://www.ncbi.nlm.nih.gov/pubmed/26116120
http://dx.doi.org/10.1186/s13550-014-0059-x