Cargando…

Maternal Hypoxia Decreases Capillary Supply and Increases Metabolic Inefficiency Leading to Divergence in Myocardial Oxygen Supply and Demand

Maternal hypoxia is associated with a decrease in left ventricular capillary density while cardiac performance is preserved, implying a mismatch between metabolism and diffusive exchange. We hypothesised this requires a switch in substrate metabolism to maximise efficiency of ATP production from lim...

Descripción completa

Detalles Bibliográficos
Autores principales: Hauton, David, Al-Shammari, Abdullah, Gaffney, Eamonn A., Egginton, Stuart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452690/
https://www.ncbi.nlm.nih.gov/pubmed/26030353
http://dx.doi.org/10.1371/journal.pone.0127424