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Maternal Hypoxia Decreases Capillary Supply and Increases Metabolic Inefficiency Leading to Divergence in Myocardial Oxygen Supply and Demand
Maternal hypoxia is associated with a decrease in left ventricular capillary density while cardiac performance is preserved, implying a mismatch between metabolism and diffusive exchange. We hypothesised this requires a switch in substrate metabolism to maximise efficiency of ATP production from lim...
Autores principales: | Hauton, David, Al-Shammari, Abdullah, Gaffney, Eamonn A., Egginton, Stuart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452690/ https://www.ncbi.nlm.nih.gov/pubmed/26030353 http://dx.doi.org/10.1371/journal.pone.0127424 |
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