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PD-1 and Tim-3 Pathways Regulate CD8(+) T Cells Function in Atherosclerosis

T cell-mediated immunity plays a significant role in the development of atherosclerosis (AS). There is increasing evidence that CD8(+) T cells are also involved in AS but their exact roles remain unclear. The inhibitory receptors programmed cell death-1 (PD-1) and T cell immunoglobulin and mucin dom...

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Detalles Bibliográficos
Autores principales: Qiu, Ming-Ke, Wang, Song-Cun, Dai, Yu-Xin, Wang, Shu-Qing, Ou, Jing-Min, Quan, Zhi-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452700/
https://www.ncbi.nlm.nih.gov/pubmed/26035207
http://dx.doi.org/10.1371/journal.pone.0128523