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MCL-1, BCL-X(L) and MITF Are Diversely Employed in Adaptive Response of Melanoma Cells to Changes in Microenvironment

Melanoma cells can switch their phenotypes in response to microenvironmental insults. Heterogeneous melanoma populations characterized by long-term growth and a high self-renewal capacity can be obtained in vitro in EGF(+)bFGF(+) medium whilst invasive potential of melanoma cells is increased in ser...

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Detalles Bibliográficos
Autores principales: Hartman, Mariusz L., Talar, Beata, Gajos-Michniewicz, Anna, Czyz, Malgorzata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452715/
https://www.ncbi.nlm.nih.gov/pubmed/26035829
http://dx.doi.org/10.1371/journal.pone.0128796