Formulation and In Vitro, In Vivo Evaluation of Effervescent Floating Sustained-Release Imatinib Mesylate Tablet

INTRODUCTION: Imatinib mesylate is an antineoplastic agent which has high absorption in the upper part of the gastrointestinal tract (GIT). Conventional imatinib mesylate (Gleevec) tablets produce rapid and relatively high peak blood levels and requires frequent administration to keep the plasma dru...

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Detalles Bibliográficos
Autores principales: Kadivar, Ali, Kamalidehghan, Behnam, Javar, Hamid Akbari, Davoudi, Ehsan Taghizadeh, Zaharuddin, Nurul Dhania, Sabeti, Bahareh, Chung, Lip Yong, Noordin, Mohamed Ibrahim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452730/
https://www.ncbi.nlm.nih.gov/pubmed/26035710
http://dx.doi.org/10.1371/journal.pone.0126874

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452730/
https://www.ncbi.nlm.nih.gov/pubmed/26035710
http://dx.doi.org/10.1371/journal.pone.0126874

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