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Modulation of Gene Expression by Polymer Nanocapsule Delivery of DNA Cassettes Encoding Small RNAs

Small RNAs, including siRNAs, gRNAs and miRNAs, modulate gene expression and serve as potential therapies for human diseases. Delivery to target cells remains the fundamental limitation for use of these RNAs in humans. To address this challenge, we have developed a nanocapsule delivery technology th...

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Detalles Bibliográficos
Autores principales: Yan, Ming, Wen, Jing, Liang, Min, Lu, Yunfeng, Kamata, Masakazu, Chen, Irvin S. Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4452785/
https://www.ncbi.nlm.nih.gov/pubmed/26035832
http://dx.doi.org/10.1371/journal.pone.0127986